Inside the chapel of the Crucifix, the work depicts the image of the Bishop Zosimus.
The figure appears standing in pontifical robes while he blesses with a mitre on his head and a pastoral staff in his left hand.
This panel has been attributed to the Sicilian painter Antonello da Messina.
The Antonellian style was in fact noted in the originality of the perspective and in the pose assumed by the three-quarter figure.
Welcomed by most critics, the attribution is, however, mitigated by the possibility of external assistance.
Moreover, this assistance is relegated to a younger artist, as shown by the uncertainty in the stylistic solutions, the rigidity of the layout and volumes and the use of a gold background.